Biogas, as one of the renewable energy sources, has become increasingly an important alternative energy source. Plants, which treat waste to produce energy, have moved to industrialized size with intensive studies in recent years. Efficiency and safe operation of these plants are very important for plants sustainability. For this purpose, safety measures must be standardized and applied to whole process from manufacturing to energy production within a biogas plant. In this study, all potential risks and necessary precautions taken against these identified risks are listed in a continuously running biogas plant. Moreover, it is also emphasized the necessity of drafting a regulation and the content of this regulation on this issue within Turkey.