© 2018 A. CARBONE Editore.Aim: Recent findings indicated that dedicated warm up activities may significantly affect performance and prevent injuries. Furthermore, since it is known that comprehensive warm up program helps in prevention injuries, the purpose of this study was to investigate the effects of a comprehensive warm-up program (F-MARC The 11+) on performance and injuries in young basketball players. While knowing the specifics and possible injuries of basketball game, the prevention of injuries must be considered as an important issue. Methods: Twenty children (mean ± SD: age 10,7 ± 0,3 yr; height 149,20 ± 7.51, weight 47,61 ± 12,30 kg, percentage of body fat: 14,44 ± 7,68 %) were recruited from two local basketball clubs to participate in this study. Players were randomly selected and assigned to either group: experimental (Exp. n = 10) or a control (Con. n = 10), respectively. They were trained 3 days per week (2,1 ± 0,6 years of experience), for 10 weeks in a row. The experimental group followed the F-MARC 11+ program for 20 minutes during warm up phase in each training season for ten weeks while control group performed their regular warm up routine. Both groups performed vertical jumps and pro agility tests at the beginning and at the end of the tenth-week training sessions. Moreover, nonparametric Wilcoxon signed rank tests were performed to compare the pre and post test scores. Results: The agility pre-test result was found 6,358 ± 0, 27 seconds and post-test was found 6,121 ± 0, 34 seconds. A significant difference was found between agility test values ( p<0,05) Discussion: Comprehensive warm-up program leads to a significant change in agility in the present study. Therefore, this is a desirable result since basketball is characterized by many quick movements such as sudden speed-ups, stops and turns. Eventually, previous studies indicated that the FIFA 11+ program resulted to be an important way to warm up properly before training sessions. Conclusion: Based on the results of this study we may conclude that "The F-MARC 11+" comprehensive warm-up is an appropriate and effective tool for improving basketball-specific performance such as agility in young basketball players.