Investigation of JC Virus Positivity By Real-time Polymerase Chain Reaction in Patients with Hematopoietic Stem Cell Transplant


ÇOLAK M. , Kocak A. A. , Kaynar L. A. , ÖZKURT Z. N. , Yegin Z. A. , BOZDAYI G.

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, cilt.25, ss.40-46, 2020 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 25 Konu: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5578/flora.68466
  • Dergi Adı: FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI
  • Sayfa Sayıları: ss.40-46

Özet

Introduction: In immunocompromised hosts, JC virus (JCV) can reactivate and cause a lytic infection of oligodendrocytes, resulting in progressive multifocal leukoencephalopathy (PML). Bone marrow is an important reservoir and possible site of neurotropic transformation for JCV. The aim of this retrospective study was to investigate the prevalance of JCV infection by real-time polymerase chain reaction (PCR) in patients sent from bone marrow transplant service to the laboratory in our hospital.