Purpose This study was conducted to evaluate a stress coping course for psychological resilience among a group of university nursing students. Design and Methods This was a quantitative study that had a pretest/posttest design without a control group. Data were collected from 78 first-year nursing students using a Stress Self-assessment Checklist and the Psychological Resilience Questionnaire (PRQ). Findings A significant increase was determined in the subscales of self-perception and social resources of PRQ following the course (P <= 0.05). Practical Implications The findings emphasized that more attention should be given to the potential role of psychological resilience in dealing with the inevitable sources of stress in the education of nursing students.