Cerebrospinal Fluid Dynamics in Patients with Multiple Sclerosis: The Role of Phase-Contrast MRI in the Differential Diagnosis of Active and Chronic Disease


ÖNER S. , KAHRAMAN A., Ozcan C., Ozdemir Z. M. , Unlu S., KAMIŞLI Ö., ...Daha Fazla

KOREAN JOURNAL OF RADIOLOGY, cilt.19, ss.72-78, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3348/kjr.2018.19.1.72
  • Dergi Adı: KOREAN JOURNAL OF RADIOLOGY
  • Sayfa Sayıları: ss.72-78

Özet

Objective: Multiple sclerosis (MS) is an inflammatory disease characterized by demyelinating plaques in the white matter. Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a new hypothesis for the etiopathogenesis of MS disease. MS-CCSVI includes a significant decrease of cerebrospinal fluid (CSF) flow through the cerebral aqueduct secondary to an impaired venous outflow from the central nervous system. This study aimed to determine whether CSF flow dynamics are affected in MS patients and the contributions to differential diagnosis in active and chronic disease using phase-contrast magnetic resonance imaging (PC-MRI).